Mrs. Little is Nicky and Becky's mother, Mr. Little's wife and a minor character in Pepper Ann. She appears more frequently than her husband.
Not a lot is known about Mrs. Little, and we never learn her first name. She mentions in "Single Unemployed Mother" that she's "worked for months on the Sorenson case" and talks about her defense and going to trial, so it can be assumed that she's some type of defense attorney.